American Association for Clinical Chemistry Annual Meeting

By Gabriel Aldaz (Director of Bay Area Office)

The American Association for Clinical Chemistry (AACC) hosted its annual scientific meeting from July 29 to August 2, 2018. An estimated 20,000 attendees walked through the doors of the McCormick Place Convention Center in Chicago, Illinois, to learn about cutting-edge technologies and new product offerings related to the field of biotech product development

Representing Simplexity Product Development were Doug Harriman (CTO), Lisa Coyne (Director of Business Development), and myself (Director of the Bay Area Office). In recent years, Simplexity has been expanding its capabilities in biotech instrumentation, and AACC gave us a first-hand look at cutting-edge technologies and new product offerings. The market leaders had impressive booths showcasing their latest diagnostic solutions, from flow cytometers to hemoglobin A1C analyzers for diabetes. We were also excited to talk to some outstanding start-ups, and even made time to meet with a few of our past and current clients who were exhibiting.

Image: Gabriel Aldaz, Lisa, Coyne, Doug Harriman

One of the most interesting trends evident at AACC is the continuing paradigm shift in healthcare delivery, extending the reach of diagnostic systems from the laboratory setting to the doctor’s office and even the home. This point-of-care testing (POCT) involves the use of portable instruments and promises rapid detection of targets, which in turn facilitates better diagnosis, shorter time-to-treatment, and more regular monitoring.

Image: FDA 

A term that is often associated with POCT is “CLIA-waived.” The Clinical Laboratory Improvement Amendments (CLIA) include waived tests, which are laboratory procedures that are so simple and accurate that it is unlikely that a methodology would be performed incorrectly. If a mistake did occur, it is also a requirement that the procedure would pose no reasonable risk of harm to a patient. CLIA-waived instruments can even be cleared by the FDA for home use. 

One example of a CLIA-waived POCT is the benchtop Cobas Liat device from Roche Diagnostics, which can be used for the detection of the influenza A, B, and Strep A viruses. Cobas Liat is a molecular diagnostic test utilizing real-time polymerase chain reaction (PCR) technology. The system includes a disposable, proprietary assay tube containing a set of chemical reagents. The sample, collected from a nasopharyngeal swab, is mixed with the reagents in a prescribed sequence, while pressure and temperature are controlled on each of the segments. Accurate results are available in under 20 minutes.

Image: Roche Cobas Liat

Interestingly, this year’s AACC Disruptive Technology Award was a competition held to recognize diagnostic developers at the forefront of POCT. Forty-two applicant companies were evaluated on the science behind their novel technologies and their potential impact on patient care. The three finalists – Ativa Medical, Two Pore Guys, and GNA Biosolutions – were selected to pitch their products.

Ativa Medical presented a fluid-processing engine integrated into a low-cost, disposable card that could enable clinics to obtain routine test results at the patient's bedside. Two Pore Guys presented a diagnostic device that uses solid-state nanopores to detect an assortment of molecules, including proteins, drugs, DNA, and RNA. However, GNA Biosolutions took top honors for its molecular diagnostic system, pulse-controlled amplification (PCA), which accelerates nucleic acid amplification. PCA could make it easier to identify individuals infected with dangerous pathogens in regions without access to hospital laboratories.

Image: Ativa Medical - MicroLAB  Image: Two Pore Guys  Image: GNA Biosolutions 

In conclusion, many of the tests that require bulky laboratory equipment will be POCT soon, thanks to advances in technology, new therapeutic options, and new care models. We look forward to seeing these advancements at AACC 2019 and to engage with new clients in the biotech instrumentation space who are seeking an outsourcing partner.

To learn more about Simplexity’s capabilities for biotech product development, download our free brochure.

company,medical,trade shows

Subscribe For More

To receive more articles like the one above in your inbox, sign-up to our newsletter below.

Blog Posts

Tech We Can’t Wait To See At CES 2019


Ossia Cota Forever Battery: Collaborative Design


Better Firmware Faster


Demystifying What it Takes to be a CEO


Considerations for Code Refactoring


American Association for Clinical Chemistry Annual Meeting


Simplexity's Answer to Growing Pains


Consumer Electronics Show 2018 | Part Three | So, What is a Robot?


Consumer Electronics Show 2018 | Part Two | CES 2018 and IoT


Consumer Electronics Show 2018 | Part One


Why on earth are heavy weights being suspended from this printer?


10 Best Places to Buy Parts for Product Development


Robust Firmware Stack Sizing


Senaptec Strobe: A Study in Simplification


Treatment, Prevention, and Medical Engineering Solutions


Options in Product Development Models: Internal, CDM, or Design Specialist


Designing Thermal Control Systems


Simplexity’s 7 Steps to Simplification©


Battle of the Buttons: UCSD vs. PSU


Considerations For Medical and Biotech Designs


Risk Mitigation in Product Design: Part 2


Risk Mitigation in Product Design: Part 1


San Diego's Biotech Consortium


Appropriate Models for 3D Motion Analysis: Part 3


University of Oregon’s Product Design Program Is One of a Kind


Appropriate Models for 3D Motion Analysis: Part 2


From Engineer to Leader: How Do You Get There?


Appropriate Models for 3D Motion Analysis: Part 1


Why Engineering Still Matters in Product Development


How Mechatronics Improve Drone Technology


Why You Need a Gyro to Measure Position


Why I, As The CEO, Get The Same Bonus As All My Other Employees


Mechatronics Aids In Embedded System Design


Top 10 Tips for Designing Injection Molded Plastic Parts


British school kids and car hackers: the widespread appeal of open source


When should you consider designing custom gears?


Conference Report: Open Source Hardware Summit


What is a Motion Control System?


The Top 10 Questions to ask a Product Development Firm


The Potential of the Apple AirPods To Disrupt A Whole Industry


How to Use Open Source Hardware in Product Development


What is the mech in mechatronics?


3 Tips for IoT Product Success


When Should I Start Designing For High-Volume Manufacturing?


Designing a 3D Printer for the Home


It Turns Out That EMC Is Not Black Magic


Selecting the correct motor type and size


When brainstorming fails, throw an imaginary cat


Five Tips for Mechatronic System Integration


Three Tips for Designing High Volume Mechatronic Products


What Is Mechatronics?


If I could only do 3 things to simplify a design, what should they be?