SAMPLE PREP TESTBED
Molecular Diagnostic Assay
Simplexity has been partnering with companies on projects to develop a consumable and instrument for a multiplex molecular diagnostic assay to test a blood sample for over 40 sepsis targets.
- In Phase 0 we developed dozens of consumable and instrument concepts and developed an overall working architecture.
- In Phase 1 we designed and built two testbed instruments around the client’s consumable concepts:
- Sample Preparation: liquid handling, temperature control, and fluid storage and handling
- Rapid PCR thermocycling
Product Requirement
Enable all assay functions, including:
- Fluid delivery via syringe / cavro pump
- Valving to select fluid path on consumable
- Heating of filter, silica bead binding chamber and elution chamber
- Mixing through sonication and shuttle mixing
- Magnetic collection of silica beads in binding chamber and elution chamber
Test Parameters
- Testing of all instrument to consumable interfaces and verified functional requirements
Hardware
- Two Sample Prep Test Rigs
Tool Operation
- Software GUI to enable workflow sequence control, temperature control, volume displacement, and path